Carcinomas are cancers that start in epithelial cells, which line organs, skin, and blood vessels. Carcinoma of unknown primary (CUP) means doctors can detect this cancer, but they cannot identify ...

If metastases occur in the body, but the original tumor remains undetectable, this is referred to as "cancer of unknown primary" (CUP). But if information on the tissue of origin is missing, neither ...

Patients with unfavorable cancer of unknown primary (CUP) lived significantly longer without disease progression when they received molecularly guided therapy (MGT) instead of chemotherapy, according ...

The enigmatic syndrome of metastatic cancer of unknown primary (CUP) site has frustrated physicians and patients for decades. There has been debate whether CUP is a single biologically distinct cancer ...

Site-specific therapy guided by gene-expressing profiling (GEP) could improve outcomes for patients with previously untreated cancers of unknown primary (CUP), Chinese researchers suggested. In their ...

MUNICH — More than two thirds of patients with cancer of unknown primary (CUP) have mutations detectable on circulating tumor DNA (ct-DNA) testing, or so-called liquid biopsy. For these patients, ...

This study is led by Dr. Zhiguo Luo (Department of Medical Oncology, Fudan University Shanghai Cancer Center). Cancer of unknown primary (CUP), a set of histologically confirmed metastases that cannot ...

Doctors are testing a new three-drug treatment that may help patients with cancer whose original source cannot be found.

In a recent study published in Nature Medicine, researchers developed a deep-learning approach for tumor origin differentiation using cytological histology (TORCH), recognizing malignancy and ...

Rachael has a degree in Zoology from the University of Southampton, and specializes in animal behavior, evolution, palaeontology, and the environment. Rachael has a degree in Zoology from the ...