Cas9 is directed to its target within the DNA sequence through the use of the guide RNA. A specific sequence of DNA that is between two and five nucleotides in length must align with the 3’ end of the ...

Researchers engineered and screened dozens of base editors to precisely target a single mutation without editing other portions of the DNA.

When scientists discovered how bacteria protect themselves against viral invaders, called phages, in the early 2000s, little ...

More than a decade ago, scientists harnessed a bacterial molecular machine that identifies and cuts specific sections of DNA, revolutionizing the ability to edit genes ...

Scientists used CRISPR/Cas9 to increase gene expression in rice by changing its upstream regulatory DNA. While other studies have used the technology to knock out or decrease the expression of genes, ...

First-mover advantages are a big deal in the world of pharmaceuticals. CRISPR Therapeutics scored the first-ever regulatory approval for a CRISPR/Cas9 treatment this month. While logistical challenges ...

Multisystemic smooth muscle dysfunction syndrome (MSMDS) is a rare condition associated with stroke, aortic dissection ...