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Professor of Biomedical Engineering, Head of Biomedical Engineering Programme, Director of CUHKSZ-Boyalife Joint Laboratory of Regenerative Medicine Engineering, Team Leader of Integrated Devices and ...
RALEIGH – In a new study, North Carolina State University researchers characterize a range of molecular tools to rewrite – not just edit – large chunks of an organism’s DNA, based on CRISPR-Cas ...
More than a decade ago, scientists harnessed a bacterial molecular machine that identifies and cuts specific sections of DNA, revolutionizing the ability to edit genes ...
Overview of CRISPR/Cas system-based tumor molecular diagnostic strategies, including variant gene, protein, and liquid biopsy marker assays and in situ molecular analysis. The CRISPR/Cas system, known ...
The CRISPR-Cas (Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR) and its associated protein (Cas9) system is a genome-editing technology that holds the potential to alleviate multiple ...
The lack of efficient delivery methods is a major barrier to clustered regularly interspaced short palindromic repeats/CRISPR-associated protein (CRISPR/Cas)-mediated genome editing in many plant ...
Another potentially game-changing discovery has come out of the lab of Feng Zhang, PhD. This time, they uncovered the first programmable RNA-guided system in eukaryotes. Just a few months ago, the ...
Zoom in of the mechanism: The RNA binding (in blue) flips the switch of the CRISPR-Cas system (in green), which activates its cutting mechanism. Disclaimer: AAAS and EurekAlert! are not responsible ...
Researchers flip nature's script by engineering a virus to carry a CRISPR system to change a bacterium's genes. Call it a CRISPR conundrum. Bacteria use CRISPR-Cas systems as adaptive immune systems ...