The axon initial segment (AIS) is a specialised domain at the proximal axon that serves as the principal site for action potential initiation and as a critical organiser of neuronal polarity. Its ...

Mentor: Joey Ransdell, Ph.D. The axon initial segment (AIS) is a distinct region in neurons vital for initiating action potentials. This is due to the high concentration of voltage-gated potassium and ...

Memories and learning processes are based on changes in the brain's neuronal connections and, as a result, in signal transmission between neurons. For the first time, DZNE researchers have observed an ...

New research reveals how a class of neurons that help coordinate communication in the brain link up with their target cells, identifying two molecules that must be present before synapses, the ...