ALS is a progressive disease, meaning it worsens over time. Although there is no cure for ALS, medications and therapies are available to help manage the symptoms, slow the disease course, and prolong ...

Researchers identify a key pathway leading to neurodegeneration in early stages of ALS, hinting at the potential for short-circuiting the progression of the fatal disease if diagnosed early.

ALS and nerve injury symptoms may feel similar. However, ALS is a progressive condition, and the symptoms people may experience typically worsen over time. In some cases, nerve injuries may trigger ...

Frontotemporal dementia worsens cognitive and behavioral difficulties and lowers life expectancy in people with ALS. It can complicate communication, daily activities, and disease management.

Diagnosing amyotrophic lateral sclerosis (ALS) involves a combination of medical history, physical exams, and various diagnostic tests to rule out other conditions. There isn’t a single definitive ...

Pictured are nuclei of induced pluripotent stem cell (iPSC)-derived motor neurons stained for contrast. The nucleus on the left has been treated with DMSO (control) and appears mostly blue. The ...