I don’t drink anymore. I don’t smoke anymore.” He might have shrugged it off, but reports accumulated in his clinic and ...

Cocaine addiction isn’t simply a failure of willpower — it’s the result of lasting biological changes in the brain.

Scientists identify the protein DeltaFosB as the "master switch" that rewires the brain's memory and reward circuits, driving chronic cocaine addiction and relapse.

Evidence is mounting that the wildly popular weight-loss medicines known as GLP-1s may also hold potential for treating addiction, and the field may be on the verge of obtaining desperately needed ...

GLP-1 medications may quiet the brain signals behind addiction, reducing substance use disorders and overdose risk across ...

A new study found GLP-1 drugs were associated with 50% fewer substance-related deaths, 39% fewer drug overdoses, and 26% ...

When a cocaine addict relapses, it isn't a matter of personal failure—it's the biological result of their brain's rewiring, ...

The gut-brain-vagal axis The vagus nerve is the main pathway of the gut-brain axis, a complex communication network linking peripheral organs to the brain by transmitting interoceptive signals about ...

Researchers identify the anterior insula as the brain region responsible for biasing decisions toward alcohol over social rewards in addiction.

People struggling with many addictions, ranging from opioids to gambling, are reporting similar experiences in clinics, on ...

Addiction is one of the most common and consequential chronic medical conditions in the United States. Nationwide, more than 46 million people met the criteria for a substance abuse disorder as of ...