Arizona had the passing game working, but it didn't matter in a 41-22 loss to San Francisco at State Farm Stadium in Glendale ...

The San Francisco 49ers had huge plays on both sides of the ball to earn a blowout win over the Arizona Cardinals. Here are ...

The two AFC West squads will face off in the desert on Sunday afternoon. After six weeks of dealing with turf toe, San Francisco 49ers quarterback Brock Purdy will be back in action on Sunday, Nov. 16 ...

Brock Purdy returned from a six-game absence to throw three touchdowns as the 49ers (7-4) romped to a 41-22 win over the host ...

Now the San Francisco 49ers look like a team that might be peaking at the right time. Purdy threw three touchdown passes, Christian McCaffrey had two rushing touchdowns and a receiving score, and the ...

ARIZONA -- The Arizona Cardinals fell to 3-7 on the season following their Week 11 loss to the San Francisco 49ers, and as the second half of the year churns forward, we still have more questions than ...

The San Francisco 49ers blew out the Arizona Cardinals, but there was a lot happening in the Week 11 matchup. Here are the ...

The Niners are coming off a win over the Arizona Cardinals in which the offense looked full-strength with Brock Purdy and ...