Week 3 of the NFL slate could feature up to five backup quarterbacks, with two set to face off in one matchup. Our betting crew will help you navigate through the unknowns and uncertainties.

Not surprisingly, the Bills are the biggest favorite (-13.5) on the Week 3 slate. Sunday afternoon features two matchups of undefeated teams, with the Philadelphia Eagles (-3.5) hosting the Los Angeles Rams and the Arizona Cardinals hitting the road to face the San Francisco 49ers (-1.5).

Click on each game for NFL Week 3 picks, NFL Week 3 predictions and NFL Week 3 odds for that game.

NFL survivor pools made it through two weeks virtually unscathed. Here are the best survivor picks for Week 3.

The Miami Dolphins put a scare into the Buffalo Bills during Thursday Night Football before quarterback Tua Tagovailoa literally threw the game away with a backbreaking interception. Miami might have played better against a good team in Buffalo,

Some of the site's predictions differ from NFL Week 3 odds and other NFL Week 3 picks for NFL Week 3 games. How correct will the analytics be this week? Click on each game for more NFL Week 3 predictions for that NFL matchup. All times MST. The site allows for the possibility of ties, so the numbers add up to just less than 100%.

The Green Bay Packers visit the Cleveland Browns in Week 3. Here is the complete roster, including jersey numbers, of all the Packers.

Week 3 is a minefield of injuries and tricky picks. Bengals vs. Vikings is one that’s very difficult to parse due to injuries to both Joe Burrow and J.J. McCarthy, making this the QB duel between Jake Browning and Carson Wentz we all expected.

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